Castiel issues a warning to Dean, Sam and Bobby; Dean winds up in a confrontation with Death; Sam struggles with the broken wall in his head.
Castiel struggles with the downside of his new power; Sam suffers from hallucinations; Bobby worries that Dean will collapse under the weight of his responsibilities.
Dean is angry when Sam disappears to pursue a case with clues identical to a mystery he encountered as a kid.
Sam and Dean discover Osiris, a vengeful Egyptian god, is responsible for a series of gruesome murders; Osiris puts Dean on trial.
Sam and Dean meet a witch whose anger over her husband's philandering has proved fatal for the townspeople.
When murderous clones of Sam and Dean are created, the Winchester brothers become wanted men; Sam and Dean turn to a quirky surveillance expert (Kevin R. McNally) for help.
Jared Padalecki
Sam Winchester
Jensen Ackles
Dean Winchester
Misha Collins
Castiel
Alexander Calvert
Jack
Mark Sheppard
Crowley