Description
RxCalc puts commonly used pharmacokinetic calculations in the palm of your hand with your iPhone or iPod Touch. The fast interface and comprehensive results help you spend less time crunching numbers and more time working on other, more important issues.
This tool is designed to help pharmacists, and physicians, quickly perform the most commonly used pharmacokinetic calculations. Calculations for designing new vancomycin and aminoglycoside dosing regimens as well as patient specific post-level adjustments to current dosing regimens are included.
What's New in Version 1.2
Release 1.2 of RxCalc adds improved functionality including:
1. Support for dosing adjustment using single level vancomycin kinetics
a. The calculations are performed using both patient specific information supplied by the user as well as patient population parameters.
2. Literature supported High Dose Extended Interval (HDEI) (aka "once daily" or "pulse") aminoglycoside dosing
b. Calculations for gentamicin and tobramycin are based on 7mg/kg adjusted body weight
c. Calculations for amikacin are based on 15mg/kg adjusted body weight
RxCalc formula/models:
1. Industry standards for ideal body weight (IBW) calculations
2. Cockcroft-Gault equation for creatinine clearance calculations
3. Vancomycin utilizes the Creighton model for calculations:
a. Kel = 0.0044 + (CrCl x 0.00083)
b. Vd = 0.7 L/kg (using actual patient body weight)
c. Vancomycin Vd is adjustable based on user need between 0.5 L/kg and 1 L/kg (default 0.7 L/kg)
4. Aminoglycoside model utilizes the following:
a. Kel = (0.14 + (0.00293 * CrCl)
b. Vd 0.26 L/kg (using adjusted patient body weight)
a. Aminoglycoside Vd is adjustable based on user need between 0.2 L/kg and 0.5 L/kg (default 0.26 L/kg)
b. Adjusted body weight for aminoglycoside calculations is calculated as follows: IBW + ((ActBW - IBW) x 0.4)
iPhone Screenshots
Customer Reviews
RxCalc
I have been a clinical pharmacist for 19-years. For the last 8-10 years, I have been using ClinRx on my palm. Unfortunately, ClinRx is not available for I-Pod/I-Phone. I misplaced my palm and was looking for an alternate program. I had seen a review from a professor at UC San Francisco praising RxCalc. I purchased this program based on that review. I found it less than useless. I plugged in the data for a large, relatively young patient with a high vancomycin trough. The data for the single level vancomycin trough provided data that was completely inaccurate. I tried again with similar data. Again, the resultant data was exactly opposite of what someone who is familiar with pharmacokinetics would expect. Example: 1500mg every 8 hours with a reported trough of 28 at 1/2 hour prior to next dose in a 128kg patient recommends a NEW dose of 1750mg every 8 hours for a goal trough of 18. If the trough is already higher than desired, why would you want to increase the dose? The original data on an actual patient provided a Tau of approximately 3 hours when the actual Tau should have been 12-18 hours.
I would not recommend this program, especially if the person purchasing the program does not have enough experience to recognize when the data being provided is not accurate.
its ok
I found that when using 2 levels to calculate phamacokinetics that the VD is way off from any equations I have seen. Also it does not extrapolate a Cmin and Cmax. This program is useful for calculating first doses. I hope this can be fixed in the next update since this is the only kinetic program I could find for the apple.
- $0.99
- Category: Medical
- Updated: Oct 07, 2010
- Version: 1.2
- Size: 0.3 MB
- Language: English
- Seller: Rob Fahrni
- © 2009-2010 Apple Core Labs, LLC
Requirements: Compatible with iPhone, iPod touch, and iPad.Requires iOS 3.0 or later
