Gastroenterology
By AGA
To listen to an audio podcast, mouse over the title and click Play. Open iTunes to download and subscribe to podcasts.
Podcast Description
An engaging, informative mix of author interviews and expert commentary on the latest articles from Gastroenterology, hosted by the AGA journals' online editor, John F. Kuemmerle, MD, AGAF.
| Name | Description | Released | Price | ||
|---|---|---|---|---|---|
|
1 |
Hepatic Cell–Type Specific Gene Expression is a Better Predictor of HCV Treatment Outcome than IL28B Genotype | Cell-type specific expression patterns of hepatic interferon-stimulated genes (ISGs) and single nucleotide polymorphisms (SNPs) near the IL28B gene are associated with response to interferon-based therapy in patients with chronic hepatitis C virus (HCV) infection. A study in the May issue of Gastroenterology finds that cell-type–specific expression pattern of ISGs varies among patients with different IL28B genotypes and is a strong predictor of response to interferon-based treatment. Dr. Kuemmerle discusses these findings with author Dr. Jordan Feld of the University of Toronto; Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 4/24/12 | Free | View In iTunes |
|
2 |
Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis | A comprehensive review article in the April issue of Gastroenterology looks at the role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis, including pathophysiology, clinical implications, and future directions. Dr. Kuemmerle speaks to author Dr. Kenneth Cusi of the University of Florida College of Medicine; Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 3/27/12 | Free | View In iTunes |
|
3 |
GC-SF Mobilizes CD34+ Cells and Improves Survival of Patients with Acute-on-Chronic Liver Failure | Acute-on-chronic liver failure (ACLF) develops in patients with chronic liver disease and has high mortality. A study in the March issue of Gastroenterology examined whether mobilization of bone marrow–derived stem cells with granulocyte colony–stimulating factor (G-CSF) might promote hepatic regeneration for patients with acute-on-chronic liver failure (ACLF). Dr. Kuemmerle speaks to author Dr. Shiv K. Sarin of GB Pant Hospital, New Delhi, India; Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 3/2/12 | Free | View In iTunes |
|
4 |
Next-Generation Stool DNA Test Accurately Detects Colorectal Cancer and Large Adenomas | Technical advances have led to stool DNA (sDNA) tests that might accurately detect neoplasms on both sides of the colorectum. A study in the February issue of Gastroenterology assessed colorectal neoplasm detection by a next-generation sDNA test and effects of covariates on test performance. Dr. Kuemmerle speaks to first author Dr. David A. Ahlquist of the Mayo Clinic, Rochester, MN; Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 2/21/12 | Free | View In iTunes |
|
5 |
Maintenance of Remission Among Patients With Crohn's Disease on Antimetabolite Therapy Following Infliximab Therapy | A study in the January issue of Gastroenterology sought to determine whether infliximab therapy can be safely interrupted in patients with Crohn's disease who have undergone a period of prolonged remission. The authors assessed the risk of relapse after infliximab therapy was discontinued in patients on combined maintenance therapy with antimetabolites and identified factors associated with relapse Dr. Kuemmerle speaks to first author Prof. Edouard Louis of the Centre Hospitalier Universitaire de Liège, Liège, Belgium; Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 12/22/11 | Free | View In iTunes |
|
6 |
Current Interferon-Free Treatment Regimens for Hepatitis C | Advances in the understanding of the hepatitis C virus (HCV) life cycle have led to the development of many promising direct-acting antiviral agents (DAA) in the last decade. An editorial in the December issue of Gastroenterology looks at the development of DAAs directed at multiple targets in the HCV life cycle and asks, “Are we ready for interferon-free treatment regimens?” Dr. Kuemmerle speaks to editorial co-author Dr. Anna S. Lok of the University of Michigan Health System; Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 12/1/11 | Free | View In iTunes |
|
7 |
Increased Risk of Nonmelanoma Skin Cancers Among Individuals With IBD | A study in the November issue of Gastroenterology looks at the risk of nonmelanoma skin cancer (NMSC) among individuals with inflammatory bowel disease (IBD), including those with or without exposure to immunosuppressant medications. Dr. Kuemmerle speaks to author Dr. Harminder Singh of the University of Manitoba; Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 11/1/11 | Free | View In iTunes |
|
8 |
Prevalence of Celiac Disease Among Patients With Nonconstipated Irritable Bowel Syndrome | A study in the October issue of Gastroenterology evaluated the prevalence of celiac disease (CD) antibodies and biopsy-confirmed CD among patients with nonconstipated irritable bowel syndrome (NC-IBS) in a large US population. Dr. Kuemmerle speaks with author Dr. Brooks D. Cash of the National Naval Medical Center, Bethesda, Maryland. Plus, a rundown of top stories from this month's issue of GI and Hepatology News | 10/1/11 | Free | View In iTunes |
|
9 |
Changes in Postprandial Lipid Clearance and Blood Glucose Homeostasis Following Vertical Sleeve Gastrectomy in Rats | Two studies in the September issue of Gastroenterology look at the effects of vertical sleeve gastrectomy (VSG) on metabolism. The first study examines whether or not beneficial effects of VSG on plasma lipid levels are weight independent. The second study investigated alterations in glucose metabolism in rats following Roux-en-Y gastric bypass (RYGB) and VSG. Dr. Kuemmerle speaks to two co-authors of both studies, Dr. Randy J. Seeley and Dr. Darleen A. Sandoval, both of the University of Cincinnati Metabolic Diseases Institute; Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 9/1/11 | Free | View In iTunes |
|
10 |
Durability of Radiofrequency Ablation in Barrett's Esophagus with Dysplasia | A study in the August issue of Gastroenterology assessed long-term rates of eradication, durability of neosquamous epithelium, disease progression, and safety of radiofrequency ablation in patients with Barrett's esophagus. Dr. Kuemmerle speaks to author Dr. Nicholas Shaheen of the University of North Carolina Chapel Hill School of Medicine and Public Health; Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 8/2/11 | Free | View In iTunes |
|
11 |
Fruit, Vegetables, and Folate: The Evidence for Cancer Prevention | Two studies in the July issue of Gastroenterology examine the relationship between fruits, vegetables, folate, and colorectal cancer, and suggest that potential associations are more complex than initially considered. Dr. Kuemmerle speaks to the author of an editorial on these papers, Dr. Andrew T. Chan of Massachusetts General Hospital; Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 7/1/11 | Free | View In iTunes |
|
12 |
Functions of Autophagy in Hepatic and Pancreatic Physiology and Disease | A review in the June issue of Gastroenterology discusses the effects of autophagy on hepatic and pancreatic physiology, and the contribution of this degradative process to diseases of the liver and pancreas. Dr. Kuemmerle speaks with author Dr. Mark Czaja of the Albert Einstein College of Medicine. Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 6/3/11 | Free | View In iTunes |
|
13 |
Aspirin or Nonsteroidal Anti-inflammatory Drug Use Increases Risk for Diverticulitis and Diverticular Bleeding | A study in the May issue of Gastroenterology examines the influence of aspirin and NSAID use on risk of diverticulitis and diverticular bleeding in a large prospective cohort. Dr. Kuemmerle speaks with author Dr. Lisa Strate of the University of Washington School of Medicine. Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 5/6/11 | Free | View In iTunes |
|
14 |
Microscopic Colitis | A comprehensive review on recent findings about the clinical features, diagnosis, epidemiology, pathophysiology, and treatment of microscopic colitis appears in the April issue of Gastroenterology. Dr. Kuemmerle speaks with a co-author of this “Reviews in Basic and Clinical Gastroenterology” article, Dr. Darrell S. Pardi of the Mayo Clinic College of Medicine, Rochester, Minnesota. Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 4/5/11 | Free | View In iTunes |
|
15 |
Management of Barrett's Esophagus | The AGA releases its medical position statement and technical review on the management of Barrett's esophagus in the March issue of Gastroenterology. Dr. Kuemmerle speaks with a co-author of both documents, Dr. John Inadomi of the University of Washington School of Medicine, about the development of the guidelines. Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 3/18/11 | Free | View In iTunes |
|
16 |
Changes in Insulin Sensitivity and Body Weight Due to Peginterferon and Ribavirin Therapy for Hepatitis C | A study in the February Gastroenterology looks at changes in insulin resistance and weight in patients with chronic hepatitis C during and after peginterferon and ribavirin therapy. Dr. Kuemmerle speaks with lead author Dr. Hari S. Conjeevaram of the University of Michigan. Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 2/18/11 | Free | View In iTunes |
|
17 |
Prevalence of NAFLD and NASH Utilizing Ultrasound and Liver Biopsy | An important prospective study in the January Gastroenterology sought to define define the prevalence of both nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) among a largely middle-aged group of outpatients. Dr. Kuemmerle speaks to author Dr. Stephen A. Harrison of the Brooke Army Medical Center in Fort Sam Houston, Texas, about the study's findings; plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 1/20/11 | Free | View In iTunes |
|
18 |
Gastrointestinal Microbial Profiles Vary With IBD Phenotypes | A Pyrosequencing study in the December Gastroenterology looked at the role of gastrointestinal microbiota in the etiology of inflammatory bowel diseases (IBD). Compositions of microbial communities were examined in 40 pairs of twins who were concordant or discordant for Crohn's disease (CD) and ulcerative colitis (UC). Dr. Kuemmerle speaks to Dr. Lars Engstrand of the Swedish Institute for Infectious Disease Control; plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 12/1/10 | Free | View In iTunes |
|
19 |
Serrated Polyps and Neoplasia | A study in the November issue of Gastroenterology investigates whether detection of proximal nondysplastic serrated polyps (ND-SP) at screening and surveillance colonoscopies is associated with advanced neoplasia. Dr. Kuemmerle speaks with author Dr. David Lieberman from the Portland VA Medical Center and Oregon Health and Science University. Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 10/29/10 | Free | View In iTunes |
|
20 |
Safety of Proton Pump Inhibitor Exposure | A review article in the October 2010 issue of Gastroenterology looks at the mechanism of action of proton pump inhibitors, summarizes the data available on the putative adverse effects of PPI therapy, and proposes guidelines for clinicians who prescribe these agents to limit the potential for adverse outcomes. Dr. Kuemmerle speaks to co-author Dr. David Metz of the University of Pennsylvania School of Medicine. Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 10/5/10 | Free | View In iTunes |
|
21 |
Acoustic Cough: Reflux Associations in Chronic Cough | Using a novel simultaneous acoustic cough recording and impedance/pH monitoring technique, the authors of a study in the September issue of Gastroenterology explored the temporal association between cough and gastroesophageal reflux (GOR) in patients in whom non-GOR causes have been excluded. Dr. Kuemmerle speaks to author Dr. Jaclyn A. Smith of the University of Manchester. Plus, a rundown of top stories from this month's issue of GI and Hepatology News. | 9/1/10 | Free | View In iTunes |
|
22 |
Achalasia: The Disease and Current Treatment | Achalasia is the subject of a mini-review article in the August issue of Gastroenterology. Dr. Kuemmerle speaks to author Dr. David Katzka of the Mayo Clinic, Rochester, MN about factors including pathophysiology, diagnosis and treatment of the disease. We also begin a new feature this month highlighting important stories and topics from the August issue of GI and Hepatology News, the AGA's official newspaper. | 7/30/10 | Free | View In iTunes |
|
23 |
Detecting Celiac Disease and Lymphocytic Enteropathy by Parallel Serology and Histopathology | A prospective study to determine the clinical, pathologic, and serologic spectrum of celiac disease in a general population appears in the July issue of Gastroenterology. Dr. Kuemmerle speaks to authors Dr. Marjorie M. Walker of Imperial College London and Dr. Joseph A. Murray of the Mayo Clinic, Rochester, Minnesota. | 6/29/10 | Free | View In iTunes |
|
24 |
Factors in the Development and Progression of Gastroesophageal Varices in Chronic Hepatitis C Patients | A study in the June 2010 issue of Gastroenterology sought to identify the incidence and predictors of de novo gastroesophageal variceal formation and progression in a large cohort of patients with chronic hepatitis C and advanced fibrosis. Dr. Kuemmerle speaks with the author of this article, Dr. Robert J. Fontana of the Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School. | 6/1/10 | Free | View In iTunes |
|
25 |
Colorectal Cancer Screening Guidelines: The Importance of Evidence and Transparency | An article in the May 2010 issue of Gastroenterology reflects on the 2008 multi-society guidelines for colorectal cancer (CRC) screening, stressing that doctors should keep an open mind and consider all evidence when deciding which test to recommend for patients. Dr. Kuemmerle speaks with the author of this “Mini-Reviews and Perspectives” article, Dr. James E. Allison, Clinical Professor of Medicine Emeritus at the University of California, San Francisco. | 4/29/10 | Free | View In iTunes |
|
26 |
Diagnosis and Treatment of Pelvic Floor Disorders | A critical review of new diagnostic and treatment innovations for pelvic floor disorders appears in the April issue of Gastroenterology. Dr. Kuemmerle speaks with author Dr. Adil E. Bharucha of the Division of Gastroenterology and Hepatology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota. | 4/1/10 | Free | View In iTunes |
|
27 |
pCLE vs. Virtual Chromoendoscopy for Colon Polyp Classification | A study in the March issue of Gastroenterology compares sensitivity and specificity of probe-based confocal laser endomicroscopy (pCLE) with that of virtual chromoendoscopy for classification of colorectal polyps. Dr. Kuemmerle discusses these findings with study author Dr. Michael Wallace of the Mayo Clinic School of Medicine, Jacksonville, FL. | 3/3/10 | Free | View In iTunes |
|
28 |
Colorectal Neoplasia in Inflammatory Bowel Disease | An AGA medical position statement and technical review on the diagnosis and management of colorectal neoplasia in inflammatory bowel disease appear in the February 2010 issue of Gastroenterology. Dr. Kuemmerle speaks with one of the authors, Dr. Francis A. Farraye of Boston University School of Medicine. | 2/1/10 | Free | View In iTunes |
|
29 |
Radioembolization for Hepatocellular Carcinoma Using Yttrium-90 Microspheres | A study in the January 2010 Gastroenterology assesses long-term clinical outcomes of Hepatocellular carcinoma patients treated with intra-arterial yttrium-90 microspheres. Dr. Kuemmerle speaks to senior author Dr. Riad Salem from the Division of Hematology and Oncology, Northwestern Memorial Hospital, Chicago, Illinois. | 12/30/09 | Free | View In iTunes |
|
30 |
Predicted Response of Chronic HBV Patients to Therapy with Peginterferon-Alfa | A study in the December 2009 Gastroenterology looks at factors that predict response of patients with chronic hepatitis B virus (HBV) infection to therapy with pegylated interferon (PEG-IFN)–alfa. Dr. Kuemmerle speaks to study author Dr. Harry Janssen of the Department of Gastroenterology and Hepatology at the University Medical Center Rotterdam. | 11/30/09 | Free | View In iTunes |
|
31 |
Gastroesophageal Reflux Might Cause Esophagitis Through a Cytokine-Mediated Mechanism Rather Than Caustic Acid Injury | A study in the November 2009 Gastroenterology looks at a possible alternative concept for the development of reflux esophagitis. Dr. Kuemmerle hosts a discussion with authors Dr. Rhonda F. Souza and Dr. Stuart J. Spechler, both of the VA North Texas Health Care System and the University of Texas Southwestern Medical School. | 10/26/09 | Free | View In iTunes |
|
32 |
Colectomy Rate Comparison After Treatment of Ulcerative Colitis With Placebo or Infliximab | A study in the October 2009 Gastroenterology compares colectomy rates following treatment of ulcerative colitis with placebo or infliximab. Dr. Kuemmerle speaks with the senior author, Dr. William Sandborn of the Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota. | 9/29/09 | Free | View In iTunes |
|
33 |
Coinfection With HIV-1 and HCV — A One-Two Punch | Dr. Arthur Kim of Massachusetts General Hospital discusses HIV-1 and HCV coinfection. This review article in the September 2009 issue of Gastroenterology examines how these viruses interact with the host immune system, with a dual focus on pathways to viral persistence and mechanisms that might underlie accelerated liver disease. | 8/31/09 | Free | View In iTunes |
|
34 |
Computed Tomographic Colonography: Current Perspectives and Future Directions | Computed tomographic (CT) colonography is the subject of an article in the “Mini-Reviews and Perspectives” section of the July 2009 issue of Gastroenterology. Dr. Kuemmerle speaks to the author, Dr. Don Rockey of University of Texas Southwestern Medical Center, about current perspectives and future directions of this fast-rising colon cancer screening method. | 8/31/09 | Free | View In iTunes |
|
35 |
Reducing Extracellular pH Sensitizes the Acinar Cell to Secretagogue-Induced Pancreatitis Responses in Rats | A new study examines whether or not exposure to an acid load might sensitize the acinar cell to secretagogue-induced pancreatitis. Dr. Kuemmerle speaks with Dr. Fred Gorelick of Yale University School of Medicine about this study in the September issue of Gastroenterology. | 8/31/09 | Free | View In iTunes |
|
36 |
Fecal Incontinence in US Adults: Epidemiology and Risk Factors | Dr. William Whitehead of the University of North Carolina at Chapel Hill discusses his study in the August 2009 issue of Gastroenterology, which set out to estimate the prevalence of different types and frequencies of fecal incontinence, describe demographic factors, and identify risk factors | 7/31/09 | Free | View In iTunes |
|
37 |
A Cost-Utility Analysis of Ablative Therapy for Barrett's Esophagus | Dr. Kuemmerle speaks with Dr. John Inadomi, author of a study in the June issue of Gastroenterology that compares the cost utility of ablation with that of endoscopic surveillance strategies. | 5/27/09 | Free | View In iTunes |
|
38 |
Heritability of Nonalcoholic Fatty Liver Disease | Dr. Kuemmerle interviews Dr. Jeffrey Schwimmer, lead author of an article in the May Gastroenterology that studies the role of familial factors in identifying individuals at high risk for NAFLD. The second of two Gastroenterology podcasts for May 2009. | 4/27/09 | Free | View In iTunes |
|
39 |
Tests of Gastric Neuromuscular Function | Dr. Kuemmerle speaks with Dr. Henry Parkman and Dr. Michael Jones, authors of a fascinating review article in the May Gastroenterology that describes tests of gastric function , provides the methodologies behind them and details the physiology that they assess, as well as their clinical utility. The first of two Gastroenterology podcasts for May 2009. | 4/27/09 | Free | View In iTunes |
|
40 |
Prospective Derivation and Validation of a Clinical Prediction Rule for Recurrent Clostridium difficile Infection | The authors of a study in the April issue of Gastroenterology have developed a clinical prediction rule for recurrent Clostridium difficile infection (CDI) that identifies high-risk patients likely to benefit from preventive measures against recurrence. Dr. Kuemmerle speaks with the senior author of the paper, Dr. Ciarán Kelly, as well as Dr. Christina Surawicz, author of a related editorial about these findings. | 3/30/09 | Free | View In iTunes |
|
41 |
A Combination of Therapies Improves Virologic Responses In Patients With Chronic Hepatitis C (Genotype 4) | Dr. Kuemmerle, Dr. Emmet Keeffe and Dr. Michael W. Fried discuss study results that show the combination of nitazoxanide, peginterferon alfa-2a, and ribavirin improved percentages of patients with rapid virologic response (RVR) and sustained virologic response (SVR). | 3/4/09 | Free | View In iTunes |
|
42 |
Infliximab Prevents Crohn's Disease Recurrence After Ileal Resection | February 2009 | 2/27/09 | Free | View In iTunes |
|
43 |
Presentation and Long Term Follow-Up of Refractory Celiac Disease - Comparison of Type I With Type II | January 2009 | 12/29/08 | Free | View In iTunes |
| Total: 43 Episodes |
Listeners also subscribed to
- DAVE Project - Gastroenterology
- Editors: Peter B. Kelsey, MD, Brenna C. Bounds, MD, G.S. Raju, MD, Dan F. Collier
- View In iTunes
- Gut podcasts
- BMJ Group
- View In iTunes
- Johns Hopkins Medicine Gastroenterology Podcasts
- Elizabeth Tracey
- View In iTunes
- PeerView Gastroenterology CME/CNE/CPE Video Podcast
- PVI, PeerView Institute for Medical Education
- View In iTunes
