Failure of Assay to Identify Low Cobalamin Concentrations (Letters) (Letter to the Editor)
Clinical Chemistry 2000, Dec, 46, 12
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To the Editor: We wish to report a serious problem in the ADVIA:Centaur[R] chemiluminescence assay for cobalamin (Bayer Diagnostics; formerly the ACS:Centaur[R] assay, Chiron Diagnostics). The problem is urgent for two reasons: (a) our findings suggest that many cobalamin-deficient patients are being missed; and (b) the assay is used by increasing numbers of laboratories, which some time ago abandoned radioisotopic methods and were recently faced with the withdrawal of widely used assays by Abbott Laboratories.
- Category: Chemistry
- Published: 01 December 2000
- Publisher: American Association for Clinical Chemistry, Inc.
- Seller: The Gale Group, Inc.
- Print Length: 9 Pages
- Language: English