Melinda Gordon communicates with earthbound spirits, ghosts who cling to the living because they have unfinished business that prevents them from moving beyond the familiar plane of existence that we call life. Inspired in part by the work of famed medium James Van Praagh and of Mary Ann Winkowski, a real-life communicator with spirits, GHOST WHISPERER explores the spiritual side of life and death as Melinda navigates among the dead and the living in her sometimes chilling, sometimes heart-rending and sometimes amusing attempts to act as an intermediary between the ghosts and those they haunt. Jim, her husband, worries about the emotional toll this work is taking on his wife as they embark on a life together. Melinda has revealed her "gift" to her friend Delia Banks, a single mom who lives in Grandview with her son, Ned, but fears the consequences of drawing her into this "unconventional" world. Melinda recently befriended Eli, a psychologist who can hear ghosts but can't see them. For her part, Melinda accepts her unique abilities as a blessing and sometime curse, but always helps her clients, alive or dead, find emotional closure.