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Use of Functionalized [Beta]-Lactams As Building Blocks in Heterocyclic Chemistry (Report)

Pure and Applied Chemistry 2010, Sept, 82, 9

Pure and Applied Chemistry

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INTRODUCTION The class of [beta]-lactam antibiotics is generally recognized as a cornerstone of human health care due to the unparalleled clinical efficacy and safety of this type of antibacterials [1]. For example, the world antibiotics market is dominated by Augmentin, a combination of amoxicillin 1 and potassium clavulanate 2, produced by GlaxoSmithKline. Nevertheless, the recent appearance of highly resistant bacteria profoundly challenges the way medicinal chemists contemplate innovation of the [beta]-lactam structure and corroborates the need for continuous efforts within this field of research.

Use of Functionalized [Beta]-Lactams As Building Blocks in Heterocyclic Chemistry (Report)
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  • 2,99 €
  • Available on iPhone, iPad, iPod touch, and Mac.
  • Category: Chemistry
  • Published: 01 September 2010
  • Publisher: International Union of Pure and Applied Chemistry
  • Print Length: 17 Pages
  • Language: English
  • Requirements: To view this book, you must have an iOS device with iBooks 1.3.1 or later and iOS 4.3.3 or later, or a Mac with iBooks 1.0 or later and OS X 10.9 or later.

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