Polymeric Delivery Systems in Biotechnology: A Mini Review (Report)
Trends in Biomaterials and Artificial Organs, 2007, July, 21, 1
Trends in Biomaterials and Artificial Organs
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Intelligent delivery devices are indispensable for the commercial realization of biotechnology based therapeutics of the post genomic era. Controlled delivery approach will enable these therapeutics to access intracellular targets without metabolic inactivation and if required achieve genomic integration, high transfection efficiency and prolonged gene expression. Implantables, micro and nanoparticulate systems in which the agent is encapsulated for nuclear delivery will have great implications in the success of recent treatment modalities like gene therapy, RNA interference and antisense oligonucleotide based gene silencing. This review compares delivery from viral vectors with non viral polymeric vectors and examines the features and suitability of various types of polymeric vectors for the delivery of therapeutic biomolecules. Introduction
- Category: Health & Fitness
- Published: Jul 01, 2007
- Publisher: Society for Biomaterials and Artificial Organs
- Seller: The Gale Group, Inc.
- Print Length: 14 Pages
- Language: English