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Treatment of Invasive Fungal Infections/Invazif Mantar Enfeksiyonlarinin Tedavisi (Report)

Journal of Pediatric Infection 2009, May

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Description

Invazif mantar enfeksiyonlari ozellikle immun sistemi baskilanmis hastalarda morbidite ve mortalitenin en onemli nedenlerinden biridir ve sikligi giderek artmaktadir (1-5). Bu enfeksiyonlarin erken ve dogru tanisi, antifungal tedavinin zamaninda baslanmasi ve gereksiz antifungal tedaviden kacinilmasi acisindan onemlidir. Ayrica dogru ve erken tani ile ampirik antifungal kullanimi azaltilarak antifungal direncin de onune gecilebilir. Invazif mantar enfeksiyonlarinin tedavisinde uzun yillar, altin standart ilac olan amfoterisin B (AmB) kullanilmistir. Daha sonralari 5-fluorositozin, itrakonazol ve flukonazol secenekleri eklenmistir. Ancak son yillarda hem kullanilan ilaclarin sayisinda hem de tedavi protokollerinde buyuk degisiklikler olmustur. Klasik ilaclarin yeni formulasyonlarinin (lipozomal AmB, lipid bazli AmB gibi) yani sira tamamen yeni grup ilaclar ile tedavi yaklasimlari da degismistir. Ayrica kombinasyon antifungal tedavileri ve konagin immun yanitini duzeltmeye yonelik tedaviler (sitotoksin tedavileri vb) de gundeme gelmistir (5-7).

Treatment of Invasive Fungal Infections/Invazif Mantar Enfeksiyonlarinin Tedavisi (Report)
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  • $5.99
  • Available on iPhone, iPad, iPod touch, and Mac.
  • Category: Health & Fitness
  • Published: May 01, 2009
  • Publisher: Aves Yayincilik
  • Seller: The Gale Group, Inc.
  • Print Length: 8 Pages
  • Language: English
  • Requirements: To view this book, you must have an iOS device with iBooks 1.3.1 or later and iOS 4.3.3 or later, or a Mac with iBooks 1.0 or later and OS X 10.9 or later.

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