DNA – an introduction
von The Open University
Dieses Kursmaterial steht nur in der iTunes U-App auf iPhone oder iPad zur Verfügung.
The mechanism of inheritance has remained one of the great puzzles of Science since Charles Darwin wrote ‘On the Origin of Species’. This learning pathway pulls together the threads of the story by linking the work of Darwin and Miescher to that of the scientist-monk Gregor Mendel in the 1860s. It looks at the detail of the structure, and how it forms the basis of a self replicating genetic system.
The pathway ends by looking at an example of where understanding DNA and inheritance is making a difference to human health, in the management of the inherited blood disorder Sickle Cell Anaemia.
|1||DNA – an introduction - video introduction||--||1:26||Gratis||In iTunes ansehen|
|2||Inheritance of characters||Genes are units of inheritance that contribute to a person’s behaviour and health. In this unit you will learn what genes, DNA and chromosomes are and how they combine to make the human genome. You will also learn how the principles of inheritance wor||--||Gratis||In iTunes ansehen|
|3||What is the genome made of?||Genomes are composed of DNA, and a knowledge of the structure of DNA is essential to understand how it can function as hereditary material. DNA is remarkable, breathtakingly simple in its structure yet capable of directing all the living processes in a||--||Gratis||In iTunes ansehen|
|4||Darwin's Burning Question||Darwin's Theory of Evolution lacked a credible explanation for characteristics which skipped generations.||4:53||Gratis||In iTunes ansehen|
|5||Mendel and Heredity||The story of Mendel who in the 1850's observed hereditary patterns in plants such as the pea.||4:28||Gratis||In iTunes ansehen|
|6||Galapagos & Nature's Variety||Darwin travels to Galapagos Islands and is confused by the variations within species such as finches.||5:29||Gratis||In iTunes ansehen|
|7||Darwinism Meets Mendelian Genetics||Only in the 1930's was it realised that it is not attributes that are passed on but genes.||6:36||Gratis||In iTunes ansehen|
|8||Miescher Identifies DNA||Miescher speculates that DNA could provide the missing piece of the puzzle of how the laws of inheritance worked physically. .||6:38||Gratis||In iTunes ansehen|
||Sickle cell disease: a lethal advantage||An introduction to the album, Sickle cell disease: a lethal advantage.||0:45||Gratis||In iTunes ansehen|
|10||The history of the sickle-shaped cell||Starting with the first diagnosis, we trace the history of sickle cell disease. We also visit the world of statistics to discover how many children are born with the illness.||5:52||Gratis||In iTunes ansehen|
|11||Sickle cell and the gene||What is sickle cell disease? And if it cannot be caught or contracted, who is at risk and what are their chances of inheriting it?||2:32||Gratis||In iTunes ansehen|
|12||Slave ships and sickle cells||Take a look at some myths surrounding the disease, and discover how genetics can explain the mysteries. Dr Anthony Allison also discusses research he conducted in Africa in 1951.||7:26||Gratis||In iTunes ansehen|
|13||Sickle cells and societies||Over the past 30 years there has been a great advancement in how sickle cell disease is treated and managed. Go behind the scenes of The Children's Hospital in Philadelphia, one of ten specialist units in the United States dealing with sickle cell resea||6:00||Gratis||In iTunes ansehen|
|14||Transmitting genetic insights||Many people have never heard of sickle cell disease. In this final track we examine how different media are being used to highlight the true nature of this disease.||6:20||Gratis||In iTunes ansehen|