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Jack Thomas is amazed to find himself the head of the company of his dreams, nestled in the high tech backdrop of beautiful Boulder, Colorado. Built with his best friend and partner Frankie, the bio-genetics company has achieved far beyond their wildest dreams. The company is poised to revolutionize the analysis and treatment of cancer and other diseases. The only thing missing is Jack's high school sweetheart, Emily, who was brutally killed, her murderer never found. Until Samantha, a beautiful green-eyed psychic haunted by Emily’s ghost, shows up. Sam takes Jack on a whirl-wind ghost chase to find Emily’s killer.With help of PIP, the sexy Artificial Intelligence assistant, Jack risks his life using the latest genetic technology to delve into a terrifying world of spirits he didn't even know existed.Genome explores the boundaries between what we can create and what we may never fully understand; science and the afterlife, chance and destiny, and a love that crosses the chasm of life and death.