Translational Medicine
By Oxford University
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Description
Research in Medicine needs to ultimately translate into better treatment of patients. Researchers at the Nuffield Department of Medicine, University of Oxford, collaborate to develop better care and improved preventive measures. Findings in the laboratory are translated into changes in clinical practice, from Bench to Bedside.
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Artemisinin Resistance | Artemisinins are very poweful tools in the treatment of malaria, and the emerging loss of their activity has the potential to create a major public health problem. MALARIA TREATMENT Dr Charlie Woodrow is based at MORU in Bangkok, Thailand, where he coo | 5 10 2015 | Free | View in iTunes |
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The ethics of research | Identifying and addressing ethical issues are key to the success of any clinical trials, particularly when working with vulnerable populations. Dr Phaik Yeong Cheah leads the Department of Bioethics & Engagement at the Mahidol Oxford Tropical Medicine R | 5 10 2015 | Free | View in iTunes |
3 |
Science and Society | In settings with high level of poverty and over-stretched health services, researchers have even greater responsibilities to the communities and study participants. SOCIAL AND BEHAVIOURAL RESEARCH A social scientist and public health researcher based | 5 10 2015 | Free | View in iTunes |
4 |
Melanoma | Melanoma or skin cancer is one of the fastest rising cancer types. When identified early, melanoma is relatively easy to cure, but once it starts to metastasise, it becomes very difficult to treat. DEREGULATION OF TRANSCRIPTION The interface between si | 5 10 2015 | Free | View in iTunes |
5 |
Targeting epigenetics to treat cancer | Transcription is a tightly regulated process, where chemical modifications initiate the duplication of genetic material. This epigenetic process is often dysregulated in cancer, but it can be targeted with small molecule inhibitors. EPIGENETIC SIGNALLIN | 5 10 2015 | Free | View in iTunes |
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A deep breath in | Asthma and COPD (chronic obstructive pulmonary disease) are common conditions that affect the lives of many people. Dr Mona Bafadhel studies the pathophysiology of COPD (chronic obstructive pulmonary disease). There are broadly two inflammatory phenotyp | 28 7 2015 | Free | View in iTunes |
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Chemistry, epigenetics and drugs | Alteration of gene expression is fundamental to many diseases. A better understanding of how epigenetic proteins affect diseases provides a starting point for therapy development and the discovery of new drug. Professor Paul Brennan research focusses on | 28 7 2015 | Free | View in iTunes |
8 |
The genetics of metabolic diseases | A missing step in a metabolic pathway leads to the build-up of toxic compounds, and the lack of materials essential for normal function. Professor Wyatt Yue explores how genetic defects lead to disease at the molecular level, by determining 3D structure | 28 7 2015 | Free | View in iTunes |
9 |
The economics of tropical diseases | Economics and health are interlinked in many ways, as seen in the vicious cycle between poverty and ill health. Dr Yoel Lubell leads the economic team at the MORU Mathematical and Economic Modelling Group, based in Bangkok, Thailand. His research focuse | 28 7 2015 | Free | View in iTunes |
10 |
Getting the dose right | Too high a dose can result in toxicity and side-effects, too low a dose can cause the illness to come back and at worse develop resistance. Professor Joel Tarning is Head of Clinical Pharmacology in our MORU Unit in Bangkok, Thailand. He's working towar | 28 7 2015 | Free | View in iTunes |
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Enteric fever | Dr Christiane Dolecek speaks about the research on enteric fever she conducted in Vietman and Nepal. Dr Christiane Dolecek's clinical research focuses on tropical diseases, in particular enteric fever and malaria. She has led enteric fever clinical tria | 20 5 2015 | Free | View in iTunes |
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Emerging Infectious Diseases | Professor Peter Horby is Senior Clinical Research Fellow. His research focusses on epidemic diseases such as Ebola and bird flu, and crosses the disciplines of basic science, medical science and public health. Influenza, SARS & Ebola Research on emergi | 11 3 2015 | Free | View in iTunes |
13 |
Human Cancer Genetics | Dr Gareth Bond, Associate Member of the Ludwig Institute for Cancer Research, studies the influence of genetic variants on the origins, progression and treatment of human cancer. SNP - single nucleotide polymorphisms There is great heterogeneity betwee | 11 3 2015 | Free | View in iTunes |
14 |
Personalised Medicine | Dr Jenny Taylor is the Programme Director for the Genomic Medicine Theme, Wellcome Trust Centre for Human Genetics. Her research bridges the gap between genetics research and the use of its discoveries in diagnosis or treatment of medical conditions. Cl | 9 2 2015 | Free | View in iTunes |
15 |
Cancer predisposition and evolution | Identifying genes that increase the risk of bowel or other cancers allows us to offer preventative measures, such as removing tumours at an early stage. A better understanding of how and why cancers grow also helps develop improved treatments. Ian Tomli | 9 2 2015 | Free | View in iTunes |
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Cancer Informatics | Cancer research now generates huge amounts of data, and sophisticated computational tools are needed to answer biological questions. Making sense of this variability at molecular level will help us better tailor treatments to individual cancer patients. | 9 2 2015 | Free | View in iTunes |
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Biological imaging | Video microscopy aims to improve target discovery and drug development and to do so generates large volumes of data. Professor Jens Rittscher has a joint appointment between the Ludwig Institute for Cancer Research, the Target Discovery Institute and th | 9 2 2015 | Free | View in iTunes |
18 |
Pharmacogenomics | Dr Sebastian Nijman develops new approaches to study signalling networks in cancer cells and uncover specific weaknesses, particularly in breast and lung cancer. This can be used to develop more effective drugs and to better guide treatment decisions. I | 9 2 2015 | Free | View in iTunes |
19 |
Microbiology in Thailand | Microbiology in Thailand Acurately diagnosing infections is particularly challenging in tropical environments. Researchers at the Mahidol Oxford Tropical Medicine Research Unit (MORU) are working to develop effective and practical means of diagnosing an | 10 12 2014 | Free | View in iTunes |
20 |
Infectious diseases in South East Asia | Infectious diseases in South East Asia The Mahidol Oxford Tropical Medicine Research Unit (MORU) is a collaboration between the University of Oxford and Mahidol University, and was established with the Wellcome Trust in 1979. MORU aims to fight the infe | 10 12 2014 | Free | View in iTunes |
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Rickettsial Disease | Daniel Paris: Rickettsial Disease Rickettsial diseases such as scrub typhus are important causes of fever in southeast Asia especially in rural communities. Discovered quite recently and not big killers, these diseases are among the most under-reported | 10 12 2014 | Free | View in iTunes |
22 |
Active and passive immunity to Influenza | Professor Townsend tells us about lessons to be drawn from the history of immunology in Oxford, from 1979 onwards, until his current research on active and passive immunity to influenza. All these developments happened in Oxford because the atmosphere w | 1 10 2013 | Free | View in iTunes |
23 |
Human Genetics | Professor Peter Donnelly tells us how genetics helps us to understand common diseases and develop new drugs. Understanding which variations in our DNA affect susceptibility to diseases can provide new insights into the disease process and lead to new tr | 9 7 2013 | Free | View in iTunes |
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The Global Health Network | Dr Trudie Lang tells us how the Global Health Network facilitates collaboration and resource sharing. Clinical trials establish the evidence base for prevention and treatment of disease and are critically important in the field of Global Health. Dr Trud | 26 6 2013 | Free | View in iTunes |
25 |
Artemisinin therapy for malaria by Professor Nick White | Professor Nick White talks about the future of artemisinin and other drug therapies for malaria. Malaria kills more than half a million people every year. Following a number of groundbreaking clinical trials, Professor Nick White and his Thailand team s | 18 6 2013 | Free | View in iTunes |
26 |
Atherosclerosis and immunity by Professor Chris O'Callaghan | Professor Chris O'Callaghan tells us about the role of our immune system in vascular disease. The accumulation of fat in the arteries, such as cholesterol, can cause a thickening of the artery wall known as atherosclerosis. Professor Chris O'Callaghan i | 11 6 2013 | Free | View in iTunes |
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Respiratory Medicine | Dr Najib Rahman talks about his research on respiratory medicine. The Pleura are thin membranes that cover the surface of the lungs. Dr Najib Rahman specialises in areas of respiratory medicine including pleural disease and the conduct and analysis of r | 28 5 2013 | Free | View in iTunes |
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Psychiatric genetics | Professor Jonathan Flint talks about his research on psychiatric genetics. It is now known that genetic variants can form the basis of psychiatric disorders, such as depression and anxiety. Professor Jonathan Flint is investigating the genetics behind p | 21 5 2013 | Free | View in iTunes |
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Development of chemical probes | Professor Stefan Knapp tells us how the development of chemical probes helps us to find new drugs. The role of proteins in cellular signalling and disease is best studied through the development of highly specific chemical inhibitors, which can serve as | 21 5 2013 | Free | View in iTunes |
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Can we block malaria transmission | Dr Sumi Biswas talks about the development of a vaccine aimed at the mosquito stage of the malaria parasite cycle. Malaria transmission-blocking vaccines aim to induce immunity against the parasites that infect mosquitoes. Such vaccines will prevent mal | 7 5 2013 | Free | View in iTunes |
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Membrane proteins and drug development | Dr Liz Carpenter talks about her research on membrane proteins and drug development. Membrane proteins are the gateways to our cells - with nutrients, waste products, and even DNA and proteins entering and leaving cells via these tightly controlled prot | 29 4 2013 | Free | View in iTunes |
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MedicineAfrica | Dr Alexander Finlayson tells us how MedicineAfrica aims to bring healthcare professionals around the world in a global expert network. Disparity in healthcare between the developed and developing world is a major global health problem. MedicineAfrica, a | 29 4 2013 | Free | View in iTunes |
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Structural cell biology of virus infection | Professor Kay Grunewald tells us how structural cell biology can help us understand virus infection. Cells constitute the smallest autonomous units of life. The tightly regulated structural and functional organisation is currently only rudimentary under | 29 4 2013 | Free | View in iTunes |
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Molecular immunology | Dr Christian Eggeling tells us how new imaging methods help us understand immunology at the molecular level. To study complex biological and immunological systems, such as living cells, scientists rely on highly sensitive and non-invasive analysis techn | 29 4 2013 | Free | View in iTunes |
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The lymphatic system in immunity and cancer | Professor David Jackson tells us about the role of the lymphatic system in immunity and cancer. The lymphatic system is a network of vessels collecting the fluids leaked from the blood vasculature. Its filtering function makes it an ideal compartment fo | 29 4 2013 | Free | View in iTunes |
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Cutaneous immunology | Professor Graham Ogg talks about the role of our skin as a barrier against infection. Skin frequently represents the first point of contact with pathogens and allergens, but there is still very little known about the role of the surface immune system in | 29 4 2013 | Free | View in iTunes |
37 |
Fiona Powrie | Professor Fiona Powrie talks about the importance of our guts, and her research in gastroenterology. | 29 4 2013 | Free | View in iTunes |
38 |
Clinical Trials in Gastroenterology | Dr Simon Travis tells us how clinical trials bring tomorrows treatments to patients today. Before translating basic research into the clinic it is important first to undergo clinical trials in order to identify safe treatments and therapies for disease. | 25 3 2013 | Free | View in iTunes |
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Cancer Immunlogy | Professor Vincenzo Cerundolo tells us how research in immunology leads to the development of new cancer treatments. Immunotherapy stimulates the bodys immune system and can be a powerful treatment for cancer. With the aim of developing better treatment | 25 3 2013 | Free | View in iTunes |
40 |
Cancer and regenerative medicine | Professor Xin Lu talks about the links between cancer and regenerative medicine. Professor Xin Lu is the Director of the Oxford branch of the Ludwig Institute for Cancer Research. Her lab works toward identifying molecular mechanisms that suppress tumou | 22 3 2013 | Free | View in iTunes |
41 |
How the immune system detects flu virus | Dr Jan Rehwinkel talks about the role of our innate immune system in our fight against flu virus. Dr Jan Rehwinkel and his group study the bodys immune reaction to viruses such as flu and HIV 1 which affect millions of people worldwide. The aim is to i | 22 3 2013 | Free | View in iTunes |
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Can we eradicate HIV? | Dr John Frater talks about his research into finding a cure for HIV. It is increasingly apparent that highly active antiretroviral therapy (HAART) may not be the long-term solution to the management of HIV infection, and that other avenues need to be ex | 12 12 2012 | Free | View in iTunes |
43 |
Viral vectored vaccine development | Professor Sarah Gilbert talks about her work on viral vectored vaccines. Professor Sarah Gilbert has been making and testing vaccines designed to induce T cell responses for ten years, chiefly using antigens from malaria and influenza. Based at the Jenn | 14 11 2012 | Free | View in iTunes |
44 |
Multiple Sclerosis | Professor Lars Fugger talks about his research on multiple sclerosis. Professor Lars Fugger focuses on translational studies in multiple sclerosis and uses a multidisciplinary approach. He is seeking to understand the molecular basis for the MHC associa | 30 10 2012 | Free | View in iTunes |
45 |
INDOX Cancer Research Network | Dr Raghib Ali talks about INDOX, the cancer research network in India. Dr Raghib Ali is the Director of INDOX Cancer Research Network. His main interest is in colorectal (bowel) cancer and other chronic, non-communicable diseases. Incidence of colorecta | 9 10 2012 | Free | View in iTunes |
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Childhood Nutrition and Immunity | Dr Jay Berkley tells us about his work on childhood nutrition and immunity in East Africa. Dr Jay Berkley works in the KEMRI/Wellcome Trust Collaborative Research Programme in Kilifi, Kenya. His research interests include tackling infection and inflamma | 25 9 2012 | Free | View in iTunes |
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Immune System in the Gastrointestinal tract | Dr Holm Uhlig talks about the role of the immune system in our gastrointestinal tract. Dr Holm Uhlig is based at the Translational Gastroenterology Unit and studies defects in the immune response and regulation leading to immunopathology. Dr Uhlig is in | 12 9 2012 | Free | View in iTunes |
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Autoimmunity | Professor Richard Cornall tells us about his research on autoimmunity. Professor Richard Cornall aims to understand the causes of autoimmune diseases. Autoimmunity occurs when the immune system which is normally designed to attack pathogens ends up atta | 12 9 2012 | Free | View in iTunes |
49 |
Progress in Malaria Vaccine Research | Dr Simon Draper tells us about his progress in malaria vaccine research. Dr Simon Draper's research interests include studies of vaccine induced malaria immunity. His group focuses on translational medicine. They will take their most promising vaccine | 11 9 2012 | Free | View in iTunes |
50 |
Rift Valley Fever | Dr George Warimwe talks about his research on Rift Valley Fever. Dr George Warimwe is working with the International Livestock Research Institute (ILRI) A Centre of Excellence in Africa, and the Jenner Institute to develop a vaccine against Rift Valley | 31 7 2012 | Free | View in iTunes |
51 |
Diabetes in Young Adults | Dr Katharine Owen talks about the different types of Diabetes in young adults. There are more forms of diabetes than the commonly known type 1 and type 2. Dr Katherine Owen investigates the different characteristics of monogenic diabetes with the aim o | 17 7 2012 | Free | View in iTunes |
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Cancer Metabolism | Dr Patrick Pollard tells us about his research on cancer metabolism. Cancer cells produce energy predominately by a high rate of glycolysis. It has been suggested that this change in metabolism is a fundamental cause of cancer. Dr Patrick Pollard aims | 10 7 2012 | Free | View in iTunes |
53 |
Diabetes and Genomics | Professor Mark McCarthy tells us how genomics helps us understand diabetes. Professor Mark McCarthy (Robert Turner Professor of Diabetes) leads a multidisciplinary research team including clinicians, nurses and lab-based research staff. One of their maj | 3 7 2012 | Free | View in iTunes |
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Universal Flu Vaccine | Dr Richard Antrobus talks about his research in the development of a universal flu vaccine. Dr Antrobus has been conducting a Phase I study of a Universal Vaccine for Influenza. Progress so far indicates that this approach induces a potent T cell respon | 26 6 2012 | Free | View in iTunes |
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Malaria vaccine for P. vivax | Dr Arturo Reyes-Sandoval tells us about his research on a vaccine against Plasmodium vivax. Dr Reyes Sandoval aims to develop a novel malaria vaccine against Plasmodium vivax, one of the four malaria parasites that affect humans. P. vivax is found in Af | 19 6 2012 | Free | View in iTunes |
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Wider Statin Use Saves Lives | Colin Baigent, Professor of Epidemiology, Clinical Trial Service Unit, Oxford, talks about why the drug Statin saves lives. | 18 6 2012 | Free | View in iTunes |
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Can we eradicate Tuberculosis? | Dr Helen Fletcher talks about progress in the development of a vaccine against tuberculosis. Dr Helen Fletcher works on multi-partner projects to discover biomarkers of protection from TB disease, develop clinical trials capacity in Africa, and develop | 12 6 2012 | Free | View in iTunes |
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Genome Integrity | Dr Opher Gileadi tells us how cells maintain genome integrity and how we can use it in our fight against cancer. Dr Opher Gileadi studies the structure and chemical biology of proteins involved in DNA repair and in recovery from DNA damage. DNA damage c | 1 6 2012 | Free | View in iTunes |
59 |
Dengue Infection | Dr Kerstin Luhn talks about her research on Dengue infection. Dr Luhn is investigating the effect of Dengue virus infection on innate immune cells to understand why Dengue, unlike other viral infections, is associated with high levels of immunopathology | 29 5 2012 | Free | View in iTunes |
60 |
HIV Vaccine Development | Professor Tomas Hanke tells us about his research on HIV vaccine development. The long term aim for Professor Tomáš Hanke is to develop a safe, effective and accessible HIV-1 vaccine. His group tests novel ideas and vaccine strategies, and focusses on | 22 5 2012 | Free | View in iTunes |
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Personalised Diabetes Treatment | Professor Stephen Gough talks about the development of personalised diabetes treatment. Prof. Stephen Gough believes that you cannot give every patient affected by diabetes the same treatment; where people react differently to treatments provides a back | 17 5 2012 | Free | View in iTunes |
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Statistical Genetics | Professor Gil McVean tells us how statistical genetics helps us understand and treat disease. Prof Gil McVean is the Head of Bioinformatics and Statistical Genetics at the Wellcome Trust Centre for Human Genetics. His research covers several areas in th | 17 5 2012 | Free | View in iTunes |
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Liver Fat Metabolism | Dr Leanne Hodson talks about her research on liver fat metabolism. Dr Leanne Hodson's research focuses on fatty liver disease, defined as having over 5 percent liver fat, and a 'silent disease' as many people are not diagnosed. Dr Hodson aims to find ta | 1 5 2012 | Free | View in iTunes |
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Metabolism of Fatty Acids | Dr Barbara Fielding talks about her research on the metabolism of fatty acids. Dr Barbara Fielding believes that nutritional advice should be based on a thorough understanding of metabolic responses to food ingestion, and that it is important to investi | 17 4 2012 | Free | View in iTunes |
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Lowering cholesterol in chronic kidney disease | The largest trial investigating the benefits of cholesterol lowering in kidney patients. The Study of Heart and Renal Protection (SHARP) concluded that around a quarter of all heart attacks, strokes, and operations to open blocked arteries could be avoi | 3 4 2012 | Free | View in iTunes |
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Hepatitis C vaccine | Dr Ellie Barnes talks about her research on Hepatitis C and her work on a T cell vaccine. Dr Ellie Barnes aims to develop a prophylactic and a therapeutic hepatitis C virus vaccine to combat a global epidemic currently infecting 170 million people world | 3 4 2012 | Free | View in iTunes |
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Genetics and Diabetes | Dr Anna Gloyn talks about her research on the genetics of Diabetes. The research undertaken by Dr Anna Gloyn focuses on using naturally genetic variants identified in humans as tools to identify critical regulatory pathways for insulin secretion and act | 20 3 2012 | Free | View in iTunes |
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Infectious diseases in China | Dr Tao Dong tells us about her collaborations in China on infections such as HIV, flu and Hepatitis B. Dr Tao Dong's research interests include antigen-specific T cell responses in human virus infections and their contribution to the consequences of the | 6 3 2012 | Free | View in iTunes |
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The treatment of severe malaria | Prof. Arjen Dondorp tells us about his work on severe malaria and the development of new therapies. Prof Arjen Dondorp is the Deputy Director and Head of Malaria Research at the Mahidol-Oxford Tropical Medicine Research Unit in Bangkok, Thailand. His ma | 21 2 2012 | Free | View in iTunes |
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HIV and children in Africa | Professor Sarah Rowland-Jones tells us about her work on HIV with children in Africa. Prof. Sarah Rowland-Jones' work mainly focuses on anti-viral immunity, and in particular how immune responses modify the outcome of HIV infection. Her research aims to | 7 2 2012 | Free | View in iTunes |
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Diabetes and Insulin Secretion | Professor Patrik Rorsman talks about Diabetes and how beta cells within the pancreas control insulin secretion. Patrik Rorsman is professor of diabetic medicine in the Oxford Centre for Diabetes, Endocrinology and Metabolism. Professor Rorsman has been | 24 1 2012 | Free | View in iTunes |
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How can we live with HIV? | Dr Lucy Dorrell tells us how our immune system controls HIV and how we can live with this virus. The aim of Dr Lucy Dorrells' research is to develop immunotherapy to reduce the dependence of those infected with HIV-1 on their current treatment - antiret | 10 1 2012 | Free | View in iTunes |
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Viruses, how to be the perfect host | Professor Paul Klenerman talks about our relationship with persistent viruses, such as Hepatitis C. Prof. Paul Klenerman studies the evolutionary relationships between persistent viruses and their human hosts. He aims to understand the role of our immun | 12 12 2011 | Free | View in iTunes |
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Genomics and Global Health | Professor Dominic Kwiatkowski talks about his work on global health, how genomics can help us fight infections such as malaria. Prof. Dominic Kwiatkowski aims to reduce the burden of infectious disease in the developing world. He translates advances in | 24 11 2011 | Free | View in iTunes |
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Specific Language Impairment | Dr Dianne Newbury talks about the contribution of genetics to specific language impairment. Dr Dianne Newbury is looking for the genes that predispose to Specific Language Impairment, a complex genetic disorder. Two regions, located on chromosomes 16 an | 14 11 2011 | Free | View in iTunes |
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HIV immunology for Vaccine Design | Dr Seph Borrow tells us how her research on HIV Immunology helps design better vaccines. There is an urgent need for vaccines to combat persistent infections like HIV. Dr Seph Borrow is studying factors affecting virus control by HIV-specific CD8+ T cel | 1 11 2011 | Free | View in iTunes |
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Renal Disease | Professor Chris Pugh tells us about the links between genetics, renal disease and oxygen sensing. The kidney plays a central role in our metabolism, by controlling various physiological balances. Genetics plays an important role in renal disease since g | 11 10 2011 | Free | View in iTunes |
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Dyslexia and Genetics | Dr Silvia Paracchini talks about the influence of Genetics in Dyslexia. Dr Silvia Paracchini aims to indentify the genetic components of dyslexia and understand the underlying biology. Other disorders such as Specific Language Impairment or Attention De | 27 9 2011 | Free | View in iTunes |
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Aiming for a HIV vaccine | Professor Sir Andrew McMichael tells us about recent developments in the search for a vaccine against HIV. Prof. Sir Andrew McMichael is working on human immunology and vaccines, first looking at flu virus and now HIV. His current lines of research incl | 13 9 2011 | Free | View in iTunes |
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Palliative Care | Dr Bee Wee tells us about Palliative Care in Oxford and her research on end of life care and fatigue. Dr Bee Wee is the Head of Palliative Care Research and Development, based at Sir Michael Sobell House in Oxford. Her current lines of research include | 30 8 2011 | Free | View in iTunes |
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Tropical Medicine in Kenya | Professor Kevin Marsh tells us about his research on Tropical Medicine in Kenya. Prof. Kevin Marsh has a broad research interest in child health in the tropics, with a particular focus in the immune epidemiology of malaria. Prof. Marsh is director of th | 19 7 2011 | Free | View in iTunes |
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Cancer and Protein Crystallography | Professor Yvonne Jones talks about cell-cell communication and how this can help us develop new drugs. Prof. Yvonne Jones is director of the Cancer Research UK Receptor Structure Research Group. Her research focuses on the structural biology of cell su | 6 7 2011 | Free | View in iTunes |
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Obesity and Diabetes | Professor Fredrik Karpe explores the links between obesity and diabetes. Prof. Fredrik Karpe initiated the Oxford Biobank for prospective genetic epidemiological research. Integrative physiological and genomic approaches are used to study lipid and carb | 21 6 2011 | Free | View in iTunes |
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Proteomics and Biomarkers | Dr Benedikt Kessler tells us how proteomics helps find biomarkers. In most living organisms, the ubiquitin-proteasome system is responsible for the degradation of proteins, either because they're damaged or they reach the end of their life span. Ubiquit | 7 6 2011 | Free | View in iTunes |
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Role of Lifestyle and Diet in Cancer | Professor Tim Key tells us about the role of life style and diet in the development of cancer. Prof. Tim Key is interested in the role of diet and hormones in the development of cancer, particularly cancers of the breast, prostate and bowel. Prof. Key i | 10 5 2011 | Free | View in iTunes |
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Autophagy | Dr Katja Simon tells us about her research on autophagy in red blood cells. Autophagy is the cellular process in which cells degrade their toxic waste and damaged organelles. Dr Katja Simon studies how the lack of autophagy seems to trigger DNA mutation | 26 4 2011 | Free | View in iTunes |
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Spondyloarthritis | Dr Paul Bowness tells us about his work on spondyloarthritis. Dr Paul Bownessis works on Ankylosing Spondylitis, the commonest form of spondyloarthritis. This rheumatic disease seems to be caused by an overacting immune system. It has a major genetic co | 12 4 2011 | Free | View in iTunes |
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Obesity and Genetics | Dr Cecilia Lindgren explores the links between obesity and genetics. Obesity and its consequences are major and growing challenges for health care worldwide. Over 30 genes associated with body mass index have now been identified. Dr Cecilia Lindgren use | 29 3 2011 | Free | View in iTunes |
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Iron Metabolism | Dr Hal Drakesmith tells us how his work on iron availability can help us fight infections. Iron plays essential biochemical roles in oxygen binding, ATP synthesis and DNA metabolism. The level of iron available in different tissues is controlled by the | 15 3 2011 | Free | View in iTunes |
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Tuberculosis | Dr Helen McShane has been working on a new TB vaccine for 10 years. She explains why developing countries are especially in need of a new vaccine since HIV and TB epidemics overlap and show a devastating synergy. There are about 9 million new cases and | 1 3 2011 | Free | View in iTunes |
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Drug Discovery | Professor Chas Bountra explains how new drugs can offer novel treatments for neurodegenerative and gastrointestinal diseases, as well as pain disorders. Professor Chas Bountra is interested in identifying and validating target proteins for drug discover | 20 12 2010 | Free | View in iTunes |
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Genetic Variation in Inflammation and Immunity | Dr Julian Knight explains how new insights into genetic variants which modulate gene expression allow us to better understand why people develop these diseases, and allow us to target treatments more effectively. Dr Julian Knight studies how genetic var | 29 11 2010 | Free | View in iTunes |
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Chromatin Remodelling | Dr Erika Mancini explains how malfunctions in the regulation of chromatin structure often leads to complex multi-system diseases and cancer, notably leukemia. Dr Erika Mancini is interested in the role of chromatin in the regulation of gene transcriptio | 15 11 2010 | Free | View in iTunes |
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Malaria and Global Health | Dr Climent Casals-Pascual explains how the development of new tools to diagnose and manage malaria more effectively will allow us to decrease the mortality of this condition. Dr Climent Casals-Pascual is interested in severe malaria, particularly its di | 2 11 2010 | Free | View in iTunes |
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Malaria Vaccines | Professor Adrian Hill has been studying the immune system and malaria susceptibility in African children for years. We asked him about his latest findings in the development of vaccines against malaria. Professor Hill develops vaccines against malaria b | 18 10 2010 | Free | View in iTunes |
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Women's Health | Dr Krina Zondervan is interested is women's health conditions, particularly endometriosis. Dr Zondervan studies genetic, molecular and environmental factors influencing this complex disorder. Women suffering from endometriosis experience severe pelvic p | 30 9 2010 | Free | View in iTunes |
96 Items |