Translational and Clinical
By Oxford University
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Description
Translational and Clinical Medicine is the ongoing effort to bring basic science from the bench to the patient, as well as to elucidate safety and effectiveness of the medicines on which we depend. The NDM podcasts on translational and clinical medicine detail our work in this wide-ranging field, from the identification and design of new medicines to clinical trials and trial design and regulation.
| Name | Description | Released | Price | ||
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1 |
A deep breath in | Asthma and COPD (chronic obstructive pulmonary disease) are common conditions that affect the lives of many people. Dr Mona Bafadhel studies the pathophysiology of COPD (chronic obstructive pulmonary disease). There are broadly two inflammatory phenotyp | 28 7 2015 | Free | View in iTunes |
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2 |
Chemistry, epigenetics and drugs | Alteration of gene expression is fundamental to many diseases. A better understanding of how epigenetic proteins affect diseases provides a starting point for therapy development and the discovery of new drug. Professor Paul Brennan research focusses on | 28 7 2015 | Free | View in iTunes |
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3 |
The genetics of metabolic diseases | A missing step in a metabolic pathway leads to the build-up of toxic compounds, and the lack of materials essential for normal function. Professor Wyatt Yue explores how genetic defects lead to disease at the molecular level, by determining 3D structure | 28 7 2015 | Free | View in iTunes |
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4 |
Biological imaging | Video microscopy aims to improve target discovery and drug development and to do so generates large volumes of data. Professor Jens Rittscher has a joint appointment between the Ludwig Institute for Cancer Research, the Target Discovery Institute and th | 9 2 2015 | Free | View in iTunes |
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5 |
Pharmacogenomics | Dr Sebastian Nijman develops new approaches to study signalling networks in cancer cells and uncover specific weaknesses, particularly in breast and lung cancer. This can be used to develop more effective drugs and to better guide treatment decisions. I | 9 2 2015 | Free | View in iTunes |
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6 |
The Global Health Network | Dr Trudie Lang tells us how the Global Health Network facilitates collaboration and resource sharing. Clinical trials establish the evidence base for prevention and treatment of disease and are critically important in the field of Global Health. Dr Trud | 26 6 2013 | Free | View in iTunes |
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7 |
Respiratory Medicine | Dr Najib Rahman talks about his research on respiratory medicine. The Pleura are thin membranes that cover the surface of the lungs. Dr Najib Rahman specialises in areas of respiratory medicine including pleural disease and the conduct and analysis of r | 28 5 2013 | Free | View in iTunes |
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8 |
Development of chemical probes | Professor Stefan Knapp tells us how the development of chemical probes helps us to find new drugs. The role of proteins in cellular signalling and disease is best studied through the development of highly specific chemical inhibitors, which can serve as | 21 5 2013 | Free | View in iTunes |
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9 |
Membrane proteins and drug development | Dr Liz Carpenter talks about her research on membrane proteins and drug development. Membrane proteins are the gateways to our cells - with nutrients, waste products, and even DNA and proteins entering and leaving cells via these tightly controlled prot | 29 4 2013 | Free | View in iTunes |
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10 |
Clinical Trials in Gastroenterology | Dr Simon Travis tells us how clinical trials bring tomorrow's treatments to patients today. Before translating basic research into the clinic it is important to first undergo clinical trials in order to identify safe treatments and therapies for disease | 25 3 2013 | Free | View in iTunes |
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11 |
Proteomics and Biomarkers | Dr Benedikt Kessler tells us how proteomics helps find biomarkers. Biomarkers are molecular features that give us clues about underlying biological processes. They are typically used to monitoring a disease or predicting the outcome of a treatment. Mode | 7 6 2011 | Free | View in iTunes |
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12 |
Drug Discovery | Professor Chas Bountra explains how new drugs can offer novel treatments for neurodegenerative and gastrointestinal diseases, as well as pain disorders. Professor Chas Bountra is interested in identifying and validating target proteins for drug discover | 20 12 2010 | Free | View in iTunes |
| 12 Items |
