Opening the iTunes Store.If iTunes doesn’t open, click the iTunes icon in your Dock or on your Windows desktop.Progress Indicator
Opening the iBooks Store.If iBooks doesn't open, click the iBooks app in your Dock.Progress Indicator

iTunes is the world's easiest way to organize and add to your digital media collection.

We are unable to find iTunes on your computer. To download from the iTunes Store, get iTunes now.

Do you already have iTunes? Click I Have iTunes to open it now.

I Have iTunes Free Download
iTunes for Mac + PC

GB Virus C / Hepatitis G Virus--Its Role in Human Disease Redefined?(Commentary)

Indian Journal of Medical Research 2007, June, 125, 6

Indian Journal of Medical Research

This book is available for download with iBooks on your Mac or iOS device, and with iTunes on your computer. Books can be read with iBooks on your Mac or iOS device.


As a result of the quest for yet unidentified viruses that cause human hepatitis, two novel flaviviruses were identified in the 1990s by two independent groups of researchers. GB virus C (GBV-C) was first identified in the sera from a West African population during an attempt to retrospectively track down the causative agent of an incident of acute hepatitis in a surgeon (whose initials were GB) (1). This new virus was however subsequently found to be unrelated to the episode of hepatitis experienced by the surgeon. Almost concurrently, hepatitis G virus (HGV) was independently cloned from the plasma of a patient with chronic hepatitis (2). Sequence comparisons of both viruses showed nucleotide and amino acid homologies of 86 and 95 per cent respectively, suggesting that they were isolates of one and the same virus (3). GBV-C/HGV infection is relatively common and has a worldwide distribution. GBV-C/HGV viraemia which is the presence of viral RNA in serum or plasma, reflects current infection. Clearance of viraemia is associated with antibody to the GBV-C/HGV envelope protein (E2) (4). Viraemia detection rates vary globally from 1 to 12.2 per cent in healthy blood donors (5,6). In this issue Kumar et al (7) report a 6 per cent viraemia rate among healthy blood donors, similar to an earlier report from this country (8). Exposure to GBV-C/HGV in a given population is the sum of the RNA and E2 antibody detection rates.

GB Virus C / Hepatitis G Virus--Its Role in Human Disease Redefined?(Commentary)
View In iTunes
  • 2,99 €
  • Available on iPhone, iPad, iPod touch, and Mac.
  • Category: Life Sciences
  • Published: 01 June 2007
  • Publisher: Indian Council of Medical Research
  • Print Length: 9 Pages
  • Language: English
  • Requirements: To view this book, you must have an iOS device with iBooks 1.3.1 or later and iOS 4.3.3 or later, or a Mac with iBooks 1.0 or later and OS X 10.9 or later.

Customer Ratings

We have not received enough ratings to display an average for this book.