Biomedical Engineering - Video
By W. Mark Saltzman
To listen to an audio podcast, mouse over the title and click Play. Open iTunes to download and subscribe to podcasts.
(BENG 100) The course covers basic concepts of biomedical engineering and their connection with the spectrum of human activity. It serves as an introduction to the fundamental science and engineering on which biomedical engineering is based. Case studies of drugs and medical products illustrate the product development-product testing cycle, patent protection, and FDA approval. It is designed for science and non-science majors. This course was recorded in Spring 2008.
|1||Video01 - What is Biomedical Engineering?||Professor Saltzman introduces the concepts and applications of biomedical engineering, providing an overview of the course syllabus, reading materials for lecture and labs and grading logistics. Various pictures are shown to highlight the current ...||10/8/2009||Free||View in iTunes|
|2||Video02 - What is Biomedical Engineering? (cont.)||Class begins with discussion of students' answers to the two questions given as assignment in the previous lecture. Professor Saltzman talks about the basic concept of biomedical engineering and two separate aspects of it: gaining better understanding...||10/8/2009||Free||View in iTunes|
|3||Video03 - Genetic Engineering||Professor Saltzman introduces the elements of molecular structure of DNA such as backbone, base composition, base pairing, and directionality of nucleic acids. He describes the processes of DNA synthesis, transcription, RNA splicing, translation, and ...||10/8/2009||Free||View in iTunes|
|4||Video04 - Genetic Engineering (cont.)||Professor Saltzman continues his presentation on DNA technology by discussing control of gene expression using two methods of RNA silencing: anti-sense therapy and RNA interference. Molecular cloning techniques to mass-produce proteins using plasmid...||10/8/2009||Free||View in iTunes|
|5||Video05 - Cell Culture Engineering||Professor Saltzman reviews the concept of gene therapy, and gives some examples of where this is applied. Methods to help deliver DNA into cells using viruses and cationic lipids are discussed, as a way to overcome some challenges in gene therapy...||10/8/2009||Free||View in iTunes|
|6||Video06 - Cell Culture Engineering (cont.)||Professor Saltzman describes the processes of fertilization and embryogenesis. Professor Saltzman then talks about the definition and classification of different types of stem cells, where stem cells are found in the body, and the potential for use of ...||10/8/2009||Free||View in iTunes|
|7||Video07 - Cell Communication and Immunology||Professor Saltzman talks about cell communication, specifically ligand-receptor interactions that are important in maintaining homeostasis in the body. Different types of receptors and ligands, the nature of their interactions and ways to apply this ...||10/8/2009||Free||View in iTunes|
|8||Video08 - Cell Communication and Immunology (cont.)||Professor Saltzman continues his discussion of cell communication in the body, extending the description to the nervous and immune system. Professor Saltzman describes the mode of signal transmission in neurons: action potential in the axon, and ...||10/8/2009||Free||View in iTunes|
|9||Video09 - Biomolecular Engineering: Engineering of Immunity||Professor Saltzman talks about the importance of vaccines, and particularly the role of bioengineering in vaccine development. He first addresses the question of "what is a vaccine" and the role of the immune system. He then describes the biological ...||10/8/2009||Free||View in iTunes|
|10||Video10 - Biomolecular Engineering: Engineering of Immunity (cont.)||Professor Saltzman continues his presentation on the topic of vaccine. First, Professor Saltzman describes the host immune response to pathogen recognition, in terms of immunoglobulin release, T-cell activation, and memory cell production...||10/8/2009||Free||View in iTunes|
|11||Video11 - Biomolecular Engineering: General Concepts||Professor Saltzman starts the lecture with an introduction to pharmacokinetics and pharmacodynamics. Professor Saltzman talks about the concept of dose-response. He introduces different routes of drug administration and how they affect drug ...||10/8/2009||Free||View in iTunes|
|12||Video12 - Biomolecular Engineering: General Concepts (cont.)||Professor Saltzman reviews the pharmacokinetic first-order rate equation that can be used to model changes in drug concentration in the blood, as well as its derivation from the law of conservation of mass. The importance of maintaining a drug ...||10/8/2009||Free||View in iTunes|
|13||Video13 - Cardiovascular Physiology||Professor Saltzman discusses the biophysics of the circulatory system. He begins by describing the anatomy of different types of blood vessels, and states the relationship between pressure difference (_P) as the driving force for fluid flow (Q) in a ...||10/8/2009||Free||View in iTunes|
|14||Video14 - Cardiovascular Physiology (cont.)||Professor Saltzman describes the blood flow through the systemic and pulmonary circulatory system. More specifically, he describes, with the help of diagrams, the events that lead to blood flow in the body as a function of contraction/relaxation by ...||10/8/2009||Free||View in iTunes|
|15||Video15 - Cardiovascular Physiology (cont.)||Professor Saltzman talks about electrical conductivity in the heart: that is, the generation and propagation of electrical potential in heart cells. He describes the role of ion channels and pumps in transporting sodium, potassium, and calcium ions to ...||10/8/2009||Free||View in iTunes|
|16||Video16 - Renal Physiology||Professor Saltzman introduces the basic concepts of renal physiology. Professor Saltzman first introduces the function and anatomy of the kidney. Special attention is given to the cell types and structural aspect of the nephron, the functional unit of ...||10/8/2009||Free||View in iTunes|
|17||Video17 - Renal Physiology (cont.)||Professor Saltzman continues his description of nephron anatomy, and the specific role of each part of the nephron in establishing concentration gradients to help in secretion and reabsorption of water, ions, nutrients and wastes. A number of molecular...||10/8/2009||Free||View in iTunes|
|18||Video18 - Biomechanics and Orthopedics||Professor Saltzman introduces the material properties of elasticity and viscosity. He describes two separate experimental setups to measure the elasticity and the viscosity of a material. Material elasticity can be defined in terms of stress-strain ...||10/8/2009||Free||View in iTunes|
|19||Video19 - Biomechanics and Orthopedics (cont.)||Professor Saltzman begins the lecture with discussion of the importance of motion for the survival and propagation of any living species. He presents the different modes of motion, taking first the example flight to talk about force balance, such as ...||10/8/2009||Free||View in iTunes|
|20||Video20 - Bioimaging||Professor Saltzman first reviews the electromagnetic spectrum, the different regimes of the spectrum, their respective wavelengths, energies, and ways of detecting them. He then talks about the use of high energy radio waves for imaging of the body...||10/8/2009||Free||View in iTunes|
|21||Video21 - Bioimaging (cont.)||Professor Saltzman continues his discussion of biomedical imaging technology. Magnetic resonance imaging (MRI) is introduced as an alternate form of imaging, which does not use ionizing radiation yet can provide detailed structure of the body...||10/8/2009||Free||View in iTunes|
|22||Video22 - Tissue Engineering||Professor Saltzman motivates the need for tissue engineering, and describes the basic elements of the tissue engineering approach. Professor Saltzman defines three different types of tissue transplants: autografts, allografts, and xenografts. An ...||10/8/2009||Free||View in iTunes|
|23||Video23 - Tissue Engineering (cont.)||In this lecture, Professor Saltzman continues his discussion of tissue engineering, and its role in facilitating healing, tissue regeneration, organ replacement, drug delivery and as model for studying human physiology. Specific examples from current ...||10/8/2009||Free||View in iTunes|
|24||Video24 - Biomedical Engineers and Cancer||Professor Saltzman uses cancer diagnosis and treatment as an example to demonstrate the some applications of biomedical engineering technologies and methods. Some issues involved in cancer treatment, such as tumor angiogenesis, radiation ...||10/8/2009||Free||View in iTunes|
|25||Video25 - Biomedical Engineers and Artificial Organs||In this final lecture, Professor Saltzman talks about artificial organs, with a stress on synthetic biomaterials. First, the body's responses (immunological and scar healing responses) to foreign materials are introduced. This leads to discussion of ...||10/8/2009||Free||View in iTunes|
Great sound - bad visuals
The lecturer has a great and simple way of explaining things. Unfortunately, the illustrations he is using throughout the lecture the whole time aren't visible for the viewer. This extremely limits the viewers understanding of the topics presented by the lecturer.
Fine lecturer, ridiculous production.
The professor is smart and clear. But he continually refers to his slides, which are not shown. All you ever see is the professor standing at the podium. What idiot at Yale thought this is the way to produce a course!!
This lecture series was life-changing. I was in college having no idea what I wanted to study and randomly stumbled upon this series of lectures on Biomedical Engineering. The topic that I found most interesting was tissue engineering. Now I'm at a top institution studying BME for my undergrad degree and loving every second of it. Had I not discovered this series of lectures I would have probably ended up with either a business degree or a biology degree.