Laurence Equilbey is best known as the music director and conductor of the popular chamber choir Accentus, which she founded in 1991. She has led this Paris-based, 32-member group in both a cappella repertory and orchestral/choral fare, but Equilbey has also branched out, especially in the new century, regularly leading operatic performances and also conducting such well-known orchestras as the Orchestre de Paris, Lyon National Orchestra, and the Orchestre National de France. In addition, she has expanded the repertory of Accentus to include transcriptions, offering such disparate fare as Wagner and Mahler lieder, Debussy's Les Angélus, Prokofiev's "Field of the Dead" from Alexander Nevsky, and many others. In 2012, Equilbey founded the period-instrument Insula Orchestra. In 2021, Equilbey led the Insula Orchestra in a recording of Louise Farrenc's Symphonies Nos. 1 and 3.