Along with cohorts Erick Morillo and Jose Nunez, Harry "Choo Choo" Romero made Subliminal Records one of the New York house community's finest. He produced numerous tracks for the label, ranging from Latin-influenced rhythms to deep, jazzy house to filter-heavy disco. Most of these gained considerable attention and club play. Even so, the success of his productions was eclipsed by that of his DJ'ing. Few New York house DJs rivaled Romero in terms of reputation, not just in New York but also in London, where Subliminal garnered a huge following.
Romero's first major hit record came in 1998, "Just Can't Get Enough," released first in the U.S. on Subliminal and then later by AM:PM in the U.K. The international success of "Just Can't Get Enough" enabled Romero to extend his popularity beyond the massive yet insular New York house community. By the end of the '90s, Romero traveled the world, spinning at clubs as far away from New York as California and Europe. The acclaim showered on Romero's approach to DJ'ing set the stage for his first high-profile DJ mix album, Subliminal Sessions, Vol. 2. Morillo's first volume in the series took a rather straightforward approach, relying heavily on the Subliminal catalog; in contrast, Romero's epic double-disc mix expanded on Morillo's volume not only in terms of scope but also chance. Where Morillo is the commercial side of Subliminal, Romero is the adventurous, daring side of the label.
Following Subliminal Sessions, Vol. 2, Romero mixed the series' seventh volume (subtitled Dirty House Music) as well as a 2007 volume of Ministry of Sound's Sessions series. He continued to release tracks on Subliminal and his own sublabel, Bambossa Records, as well as other labels such as Ovum, Circus Recordings, and Strictly Rhythm.