Vancomycin Calculator by ClinCalc
By ClinCalc LLC
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Advanced vancomycin pharmacokinetics calculator designed for pharmacists and physicians. Includes a variety of dosing strategies and calculation methods to determine an optimal vancomycin dose using standard pharmacokinetic equations.
- Calculate a vancomycin dose based on creatinine clearance, one trough level, or two vancomycin levels
- Specify one of three therapeutic goals (Trough 15-20, Trough 10-15, or AUC:MIC > 400)
- Customize default infusion times, organism MIC, volume of distribution, and creatinine assay method (including IDMS)
- Dynamically change dose, frequency, infusion time, or volume of distribution and evaluate the change in drug concentration in real-time
This tool is provided for educational purposes only. This mobile application is not intended for use in the diagnosis of disease or other conditions, or in the cure, mitigation, treatment, or prevention of disease, in man or other animals.
What's New in Version 3.2
3.2 - Slight change in the vancomycin calculation equations to account for drug elimination during drug infusion (matching the same algorithm on ClinCalc.com); minor bug fixes
Excellent iPhone application if you dose vancomycin from the bedside
I purchased this application to support the developer. You can get the same calculations from the excellent free website which also has other medical calculators. I would like to see the developer offer an iPhone medical calculator that has all of the calculators from the website. A built-in tutorial would be useful but if you play around with the application you'll find it intuitive.
Only accurate in 'normal' patients
The vanco PK model used by this app is pretty good for patients with normal body weight, but does not accurately calculate V or K in obese or underweight patients. As a result, doses are too high in obese patients and too low in underweight patients. Use of adjusted BW to calculate CrCl has not been studied in vanco PK. Instead of using the shortcut Matzke equation for K, a better approach may be to use a full PK model which first calculates vanco clearance, then calculates K as : K = CLvanco/ V. If interested in a full PK method, refer to Murphy 2006 article in AJHP 'a comparison of 7 vanco PK models'. In the patient population at the hospital where I work, the Bauer method (from his book Applied Clinical PK by Larry Bauer) is the most accurate for estimating initial doses.
Great app. Every pharmacist should have it
Every pharmacist should have it
- Category: Medical
- Updated: Aug 13, 2015
- Version: 3.2
- Size: 5.6 MB
- Language: English
- Seller: ClinCalc LLC
- ©2015 - ClinCalc LLC
Compatibility: Requires iOS 6.0 or later. Compatible with iPhone, iPad, and iPod touch.