Eighteen-year-old Jenny Morton has a horrific secret: her touch spreads a deadly supernatural plague, the "Jenny pox." She lives by a single rule: Never touch anyone. A lifetime of avoiding any physical contact with others has made her isolated and painfully lonely in her small rural town.
Then she meets the one boy she can touch, and her life begins to change. Jenny feels herself falling for him, but first Jenny must learn to use the deadly pox inside her to confront her new enemy, a girl who secretly wields the most dangerous power of all.