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Fragile Beginnings

Discoveries and Triumphs in the Newborn ICU

This book can be downloaded and read in iBooks on your Mac or iOS device.


This is a gripping medical narrative that brings readers into the complex world of newborn intensive care, where brilliant but imperfect doctors do all they can to coax life into their tiny, injured patients. Dr. Adam Wolfberg--journalist, physician specializing in high-risk pregnancies, and father to a child born weighing under two pounds--describes his daughter Larissa's precipitous birth at six months, which left her tenuously hanging on to life in an incubator. Ultrasound had diagnosed a devastating hemorrhage in her brain that doctors reasoned would give her only a 50 percent chance of having a normal IQ. With the knowledge that their daughter could be severely impaired for life, Adam and his wife, Kelly, consider whether to take Larissa off life-support.

As they make decisions about live-saving care in the first hours of a premature infant's life, doctors and parents must grapple with profound ethical and scientific questions: Who should be saved? How aggressively should doctors try to salvage the life of a premature baby, who may be severely neurologically and physically impaired? What will that child's quality of life be like after millions of dollars are spent saving him or her? Wolfberg explores the fits and starts of physicians, government policy makers, and lawyers who have struggled over the years to figure out the best way to make these wrenching decisions. 

Through Larissa's early hospital course and the struggle to decide what is best for her, Wolfberg examines the limitations of newborn intensive-care medicine, neuroplasticity, and decision making at the beginning of life.  Featuring high-profile scientific topics and explanatory medical reporting, this is the first book to explore the profound emotional and ethical issues raised by advancing technology that allows us to save the lives of increasingly undeveloped preemies.

From Publishers Weekly

Sep 19, 2011 – They are the littlest patients, facing daunting survival odds and, if they beat those, a lifetime of physical and mental hurdles. But the stories of extremely premature infants the 2% born before 32 weeks of gestation could have no better narrator than Wolfberg, a Tufts Medical Center obstetrician. Wolfberg s own daughter, Larissa, was born three months prematurely, and is the focus of this astounding history of the advances in neonatal medical care, and understanding the brain s ability to adapt to injury. This story is one of hope: the death rate for very premature babies has fallen dramatically thanks to groundbreaking advances in preventing the collapse of immature lungs and better use of oxygen, among others. Yet the challenges still remaining are daunting, particularly complications that cause cerebral palsy. Wolfberg describes research holding great promise and reviews the ethics of caring for infants whose hold on life is so tenuous, showing how the environment of the newborn nursery has shifted from one in which caregivers and parents had autonomy in decision-making to one open to controversy, disagreements, and court intervention. Wolfberg celebrates each milestone in this important field of medicine and in nine-year-old Larissa s remarkable life.
Fragile Beginnings
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  • $23.99
  • Available on iPhone, iPad, iPod touch, and Mac.
  • Category: Medical
  • Published: Feb 07, 2012
  • Publisher: Beacon Press
  • Seller: Penguin Random House LLC
  • Print Length: 176 Pages
  • Language: English
  • Requirements: To view this book, you must have an iOS device with iBooks 1.3.1 or later and iOS 4.3.3 or later, or a Mac with iBooks 1.0 or later and OS X 10.9 or later.

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