iTunes

Opening the iTunes Store.If iTunes doesn't open, click the iTunes application icon in your Dock or on your Windows desktop.Progress Indicator
Opening the iBooks Store.If iBooks doesn't open, click the iBooks app in your Dock.Progress Indicator
iTunes

iTunes is the world's easiest way to organize and add to your digital media collection.

We are unable to find iTunes on your computer. To download from the iTunes Store, get iTunes now.

Already have iTunes? Click I Have iTunes to open it now.

I Have iTunes Free Download
iTunes for Mac + PC

Velocardiofacial Syndrome--a Syndrome with Many Faces (Case Study)

South African Journal of Psychiatry 2011, August, 17, 3

South African Journal of Psychiatry

This book is available for download with iBooks on your Mac or iOS device, and with iTunes on your computer. Books can be read with iBooks on your Mac or iOS device.

Description

Among the many features with which velocardiofacial syndrome (VCFS) may present, we review in this paper the literature on working memory deficits, dysmorphic features, co-morbid obsessive-compulsive disorder, early deviant behaviour, functional impairment, and early age of onset of schizophrenia. These features are considered in a case series of 5 patients, and in addition we report on uncommon features. We highlight the importance of appropriate genetic counselling and need for preventive treatments in the future. Considering that covert symptoms in VCFS may easily be overlooked, we call for clinical vigilance in detecting VCFS among patients suffering from schizophrenia using the Bassett and Chow criteria, because the diagnosis of VCFS is of importance in determining prognosis and providing appropriate genetic counselling. MERGEFIELD background Velocardiofacial syndrome (VCFS), also known as DiGeorge or Shprintzen syndrome, is associated with small deletions of chromosome 22q11. It was first described by Shprintzen et al. and has an estimated prevalence of 1 in 5 950 births, making it the second most common genetic syndrome after Down syndrome. (1,2) It has been shown that patients with a hemizygous deletion of the q11 band of chromosome 22 are at a high risk of serious psychiatric illnesses, schizophrenia being the most common of these. (3-8) They have a 29 times higher risk than the general population of developing schizophrenia and 3 times the risk of having a first-degree relative with schizophrenia. (8,9) The familial pattern of schizophrenia has been recognised for a long time. (1,10-12) The 22q11 deletion syndrome (DS) occurs most frequently as a sporadic mutation in schizophrenia, but inheritance plays a role in 10% of cases.

Velocardiofacial Syndrome--a Syndrome with Many Faces (Case Study)
View In iTunes
  • $5.99
  • Available on iPhone, iPad, iPod touch, and Mac.
  • Category: Health & Fitness
  • Published: Aug 01, 2011
  • Publisher: South African Medical Association
  • Seller: The Gale Group, Inc.
  • Print Length: 19 Pages
  • Language: English
  • Requirements: To view this book, you must have an iOS device with iBooks 1.3.1 or later and iOS 4.3.3 or later, or a Mac with iBooks 1.0 or later and OS X 10.9 or later.

Customer Ratings

We have not received enough ratings to display an average for this book.