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Molecular Epidemiology of Infectious Diseases

by The Ohio State University

This course material is only available in the iTunes U app on iPhone or iPad.

Course Description

This course provides a comprehensive overview and detailed discussion on the core molecular approaches that are used in addressing infectious disease issues in the population medicine context. Application of molecular approaches are essential to determine etiology, understand transmission patterns, tracking sources of outbreaks and timely control of outbreaks and prevention of infectious diseases. In this course, theoretical and practical aspects of various genotyping methods will be discussed in the context of epidemiological problems. Key aspects of the course will also include:
  • Lecture topics will cover the principles and application of various molecular techniques; appropriate selection of genotyping, data analysis, interpretation and trouble shooting. 
  • This course is given for the first time by global experts from academia and industry groups spanning from the laboratory bench top in the united States; to hospital beds and field settings in global locations including sub Saharan Africa (such as Tanzania) and also Latin America (mainly Brazil). Experts participating in this course include from Brazil; Belgium; Tanzania and United States (California, North Carolina and Ohio). Therefore, the course is truly of global nature. 
  • This course addresses major global infectious disease issues such as Tuberculosis; Multi-drug resistant Foodborne pathogens; Tickborne diseases and other nosocomial and community-acquired infections of public health significance.
  • Detailed overviews of analytic approaches and bioinformatic tools including Suparamap and Bionumerics are also described in detail by lead experts including Applied Maths group. These materials will also be supported with literature review and critiques.

Course objectives:
After taking this class, participants are expected to be able to understand the key molecular approaches useful for epidemiologic investigations and will be able to integrate molecular biology approaches into epidemiological investigations.
  • Students will learn a variety of existing and emerging molecular tools that can be applied to epidemiological studies of infectious diseases.
  • Students will be able to use molecular approaches to design and implement epidemiological studies to investigate problems of infectious diseases.
  • Students will have a broad understanding of how they make choices of genotyping approaches; the pros and cons of each method; the detailed principles of each and the purposes for using specific genotypic approaches;
  • Students will understand the advantages and limitations of each molecular technique and will be able to make a critical analysis and interpretation of data collected with various molecular approaches.
Molecular Epidemiology of Infectious Diseases
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