This season, Dr. Will Halstead (Nick Gehlfuss) has to balance the stress as the ER’s supervising Attending Physician while exploring a budding romance with Dr. Natalie Manning (Torrey DeVitto), emergency pediatrics resident. Rising star heart surgeon Dr. Connor Rhodes’ (Colin Donnell) skills are put to the test with the arrival of a new, highly competitive Cardiothoracic Fellow, Dr. Ava Bekker (guest star Norma Kuhling). Dr. Daniel Charles (Oliver Platt) recovers from both the physical and psychological injuries from being shot, but still remains the Sherlock Holmes of psychiatry. Dr. Sarah Reese (Rachel DiPillo) continues her psychiatry residency under Dr. Charles, despite new reservations in the wake of her mentor’s assault. Former Navy flight surgeon Dr. Ethan Choi (Brian Tee) brings his battlefield skills to the front lines of Chicago’s busiest ER, the go-to place for victim’s of the city’s gun violence. Sharon Goodwin (S. Epatha Merkerson), the venerable head of Chicago Med, balances the pressure of keeping the city’s largest hospital afloat while maintaining an atmosphere of quality care and compassion. April Sexton (Yaya DaCosta) is a smart, bold and intuitive ER nurse navigating the hospital politics of dating a doctor and co-worker. Maggie Lockwood (Marlyne Barrett) is the confident charge nurse and the eyes, ears and brain of the emergency department. Joining the team this season is rival Dr. Ava Bekker, a perennial thorn in the side of Dr. Rhodes while his girlfriend and epidemiologist Robin Charles (guest star Mekia Cox) recovers from her rare illness. April’s ambitious brother Noah Sexton (guest star Roland Buck III) joins the ER as its newest physician. Together, they will confront Chicago’s most critical medical cases and challenging ethical dilemmas with courage, compassion and state-of-the-art treatment. Inspired by ripped-from-the-headlines cases, "Chicago Med" will weave cutting-edge medicine with the personal drama that comes with working in such a high-intensity environment. Through it all, familiar faces from "Chicago Fire," and "Chicago P.D" will intertwine with Chicago’s finest medical heroes.